Transcriptional network analysis of human astrocytic endfoot genes reveals region-specific associations with dementia status and tau pathology

The deposition of misfolded proteins, including amyloid beta plaques and neurofibrillary tangles is the histopathological hallmark of Alzheimer’s disease (AD). The glymphatic system, a brain-wide network of perivascular pathways that supports interstitial solute clearance, is dependent upon expressi...

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Detalles Bibliográficos
Autores principales: Simon, Matthew J., Wang, Marie X., Murchison, Charles F., Roese, Natalie E., Boespflug, Erin L., Woltjer, Randall L., Iliff, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098119/
https://www.ncbi.nlm.nih.gov/pubmed/30120299
http://dx.doi.org/10.1038/s41598-018-30779-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098119/
https://www.ncbi.nlm.nih.gov/pubmed/30120299
http://dx.doi.org/10.1038/s41598-018-30779-x

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