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Multicilin and activated E2f4 induce multiciliated cell differentiation in primary fibroblasts
Multiciliated cells (MCCs) are specialized epithelial cells that project hundreds of motile cilia. To form these cilia, MCCs differentiate by dramatically expanding centriole number, using assembly factors required for centriole duplication during the cell cycle and multiple, novel assembly sites, c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098136/ https://www.ncbi.nlm.nih.gov/pubmed/30120325 http://dx.doi.org/10.1038/s41598-018-30791-1 |