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Predictors of mosaic chromosome Y loss and associations with mortality in the UK Biobank

Mosaic loss of the Y chromosome (mLOY) is the most commonly reported large structural somatic event. Previous studies have indicated age and cigarette smoking increase the risk of mLOY, but the relationship of other exposures with mLOY and mLOY with disease has not been adequately investigated. We c...

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Detalles Bibliográficos
Autores principales: Loftfield, Erikka, Zhou, Weiyin, Graubard, Barry I., Yeager, Meredith, Chanock, Stephen J., Freedman, Neal D., Machiela, Mitchell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098142/
https://www.ncbi.nlm.nih.gov/pubmed/30120341
http://dx.doi.org/10.1038/s41598-018-30759-1