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Interaction of septin 7 and DOCK8 in equine lymphocytes reveals novel insights into signaling pathways associated with autoimmunity

The GTP-binding protein septin 7 is involved in various cellular processes, including cytoskeleton organization, migration and the regulation of cell shape. Septin 7 function in lymphocytes, however, is poorly characterized. Since the intracellular signaling role of septin 7 is dependent on its inte...

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Detalles Bibliográficos
Autores principales: Schauer, Melanie, Kleinwort, Kristina J. H., Degroote, Roxane L., Wiedemann, Carmen, Kremmer, Elisabeth, Hauck, Stefanie M., Deeg, Cornelia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098150/
https://www.ncbi.nlm.nih.gov/pubmed/30120291
http://dx.doi.org/10.1038/s41598-018-30753-7