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Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence

Methods for site-selective chemistry on proteins are in high demand for the synthesis of chemically modified biopharmaceuticals, as well as for applications in chemical biology, biosensors and more. Inadvertent N-terminal gluconoylation has been reported during expression of proteins with an N-termi...

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Detalles Bibliográficos
Autores principales: Martos-Maldonado, Manuel C., Hjuler, Christian T., Sørensen, Kasper K., Thygesen, Mikkel B., Rasmussen, Jakob E., Villadsen, Klaus, Midtgaard, Søren R., Kol, Stefan, Schoffelen, Sanne, Jensen, Knud J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098153/
https://www.ncbi.nlm.nih.gov/pubmed/30120230
http://dx.doi.org/10.1038/s41467-018-05695-3