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Conditional control of fluorescent protein degradation by an auxin-dependent nanobody

The conditional and reversible depletion of proteins by auxin-mediated degradation is a powerful tool to investigate protein functions in cells and whole organisms. However, its wider applications require fusing the auxin-inducible degron (AID) to individual target proteins. Thus, establishing the a...

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Detalles Bibliográficos
Autores principales: Daniel, Katrin, Icha, Jaroslav, Horenburg, Cindy, Müller, Doris, Norden, Caren, Mansfeld, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098157/
https://www.ncbi.nlm.nih.gov/pubmed/30120238
http://dx.doi.org/10.1038/s41467-018-05855-5