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Chronic cannabis promotes pro-hallucinogenic signaling of 5-HT2A receptors through Akt/mTOR pathway

Long-term use of potent cannabis during adolescence increases the risk of developing schizophrenia later in life, but to date, the mechanisms involved remain unknown. Several findings suggest that the functional selectivity of serotonin 2A receptor (5-HT2AR) through inhibitory G-proteins is involved...

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Detalles Bibliográficos
Autores principales: Ibarra-Lecue, Inés, Mollinedo-Gajate, Irene, Meana, J Javier, Callado, Luis F, Diez-Alarcia, Rebeca, Urigüen, Leyre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098160/
https://www.ncbi.nlm.nih.gov/pubmed/29748632
http://dx.doi.org/10.1038/s41386-018-0076-y