Mutagenicity and teratogenicity studies of vitacoxib in rats and mice

Vitacoxib is a new drug candidate for treatment of inflammation, pain and fever as selective cyclooxygenase-2 inhibitors. In the current study, the mice sperm abnormality, mammalian erythrocyte micronucleus and in vivo chromosome aberration, and teratogenicity in SD rats were evaluated. Vitacoxib di...

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Detalles Bibliográficos
Autores principales: Wang, Jianzhong, Sun, Feifei, Tang, Shusheng, Zhang, Suxia, Li, Jing, Cao, Xingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098211/
https://www.ncbi.nlm.nih.gov/pubmed/30128300
http://dx.doi.org/10.1016/j.toxrep.2018.08.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098211/
https://www.ncbi.nlm.nih.gov/pubmed/30128300
http://dx.doi.org/10.1016/j.toxrep.2018.08.007

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