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Apigenin Inhibits UVB-Induced Skin Carcinogenesis: The Role of Thrombospondin-1 as an Anti-Inflammatory Factor

We have previously demonstrated that apigenin promotes the expression of antiangiogenic protein thrombospondin-1 (TSP1) via a mechanism driven by mRNA-binding protein HuR. Here, we generated a novel mouse model with whole-body THBS-1 gene knockout on SKH-1 genetic background, which allows studies of...

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Detalles Bibliográficos
Autores principales: Mirzoeva, Salida, Tong, Xin, Bridgeman, Bryan B., Plebanek, Michael P., Volpert, Olga V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098219/
https://www.ncbi.nlm.nih.gov/pubmed/30118999
http://dx.doi.org/10.1016/j.neo.2018.07.005