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The phenomena of balanced effect between α-globin gene and of β-globin gene

BACKGROUND: Thalassemias (TM) are the most common autosomal recessive disorders in Southeast Asian countries. Both α- and β-thalassemia lead to a decrease or absence of globin chains. The most serious of the thalassemia syndromes is thalassemia major which is characterized by a transfusion dependent...

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Detalles Bibliográficos
Autores principales: Zhong, Liangying, Gan, Xin, Xu, Lingling, Liang, Chujia, Xie, Yingjun, Lin, Wenbin, Chen, Peisong, Liu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098578/
https://www.ncbi.nlm.nih.gov/pubmed/30119651
http://dx.doi.org/10.1186/s12881-018-0659-9