Amyloid-β interrupts canonical Sonic hedgehog signaling by distorting primary cilia structure

BACKGROUND: Primary cilia are small non-motile microtubule and cell membrane protrusions expressed on most vertebrate cells, including cortical and hippocampal neurons. These small organelles serve as sensory structures sampling the extracellular environment and reprogramming the transcriptional mac...

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Detalles Bibliográficos
Autores principales: Vorobyeva, Anna G., Saunders, Aleister J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098584/
https://www.ncbi.nlm.nih.gov/pubmed/30140428
http://dx.doi.org/10.1186/s13630-018-0059-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098584/
https://www.ncbi.nlm.nih.gov/pubmed/30140428
http://dx.doi.org/10.1186/s13630-018-0059-y

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