Cargando…
Amyloid-β interrupts canonical Sonic hedgehog signaling by distorting primary cilia structure
BACKGROUND: Primary cilia are small non-motile microtubule and cell membrane protrusions expressed on most vertebrate cells, including cortical and hippocampal neurons. These small organelles serve as sensory structures sampling the extracellular environment and reprogramming the transcriptional mac...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098584/ https://www.ncbi.nlm.nih.gov/pubmed/30140428 http://dx.doi.org/10.1186/s13630-018-0059-y |