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lncRNA KRAL reverses 5-fluorouracil resistance in hepatocellular carcinoma cells by acting as a ceRNA against miR-141

BACKGROUND: 5-Fluorouracil (5-FU) has been widely applied to treat various types of cancers, including hepatocellular carcinoma (HCC). However, primary or acquired 5-FU resistance prevents the clinical application of this drug in cancer therapy. Herein, our study is the first to demonstrate that low...

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Detalles Bibliográficos
Autores principales: Wu, Lili, Pan, Chenwei, Wei, Xin, Shi, Yifen, Zheng, Jianjian, Lin, Xiangyang, Shi, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098660/
https://www.ncbi.nlm.nih.gov/pubmed/30119680
http://dx.doi.org/10.1186/s12964-018-0260-z