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Activation of Phosphotyrosine-Mediated Signaling Pathways in the Cortex and Spinal Cord of SOD1(G93A), a Mouse Model of Familial Amyotrophic Lateral Sclerosis
Degeneration of cortical and spinal motor neurons is the typical feature of amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease for which a pathogenetic role for the Cu/Zn superoxide dismutase (SOD1) has been demonstrated. Mice overexpressing a mutated form of the SOD1 gene...
Autores principales: | Mallozzi, Cinzia, Spalloni, Alida, Longone, Patrizia, Domenici, Maria Rosaria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098854/ https://www.ncbi.nlm.nih.gov/pubmed/30154836 http://dx.doi.org/10.1155/2018/2430193 |
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