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Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation

Some iron chelators display significant anticancer activity that may involve ferritin degradation either in proteasomes or in lysosomes, and the latter might involve ferritinophagy with a period. However, the correlation of ferritinophagy with anticancer activity of iron chelator was not fully deter...

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Detalles Bibliográficos
Autores principales: Huang, Tengfei, Sun, Yanjie, Li, Yongli, Wang, Tingting, Fu, Yun, Li, Cuiping, Li, Changzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098875/
https://www.ncbi.nlm.nih.gov/pubmed/30154950
http://dx.doi.org/10.1155/2018/4928703