Cargando…
Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation
Some iron chelators display significant anticancer activity that may involve ferritin degradation either in proteasomes or in lysosomes, and the latter might involve ferritinophagy with a period. However, the correlation of ferritinophagy with anticancer activity of iron chelator was not fully deter...
Autores principales: | Huang, Tengfei, Sun, Yanjie, Li, Yongli, Wang, Tingting, Fu, Yun, Li, Cuiping, Li, Changzheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098875/ https://www.ncbi.nlm.nih.gov/pubmed/30154950 http://dx.doi.org/10.1155/2018/4928703 |
Ejemplares similares
-
DpdtC-Induced EMT Inhibition in MGC-803 Cells Was Partly through Ferritinophagy-Mediated ROS/p53 Pathway
por: Feng, Jiankang, et al.
Publicado: (2020) -
The novel dithiocarbamate, DpdtC suppresses HER2-overexpressed cancer cells by up-regulating NDRG1 via inactivation of HER2-ERK 1/2 signaling
por: Yang, Yun, et al.
Publicado: (2018) -
Ferritinophagy-Mediated ROS Production Contributed to Proliferation Inhibition, Apoptosis, and Ferroptosis Induction in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate Acetate
por: Li, Longlong, et al.
Publicado: (2021) -
Ferritinophagic Flux Activation in CT26 Cells Contributed to EMT Inhibition Induced by a Novel Iron Chelator, DpdtpA
por: Sun, Yanjie, et al.
Publicado: (2019) -
p53-Mediated PI3K/AKT/mTOR Pathway Played a Role in Ptox(Dpt)-Induced EMT Inhibition in Liver Cancer Cell Lines
por: Li, Yongli, et al.
Publicado: (2019)