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Alu hypermethylation and high oxidative stress in patients with musculoskeletal tumors

BACKGROUND: Alu is one of the non-autonomous element retrotransposons, constituting nearly 11% of the human DNA. Methylation changes of the Alu element can cause genomic instability, a hallmark of cancer development, ultimately leading to the development of cancer. Epigenetic factors may induce the...

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Detalles Bibliográficos
Autores principales: Woraruthai, Thamonwan, Charoenlap, Chris, Hongsaprabhas, Chindanai, Mutirangura, Apiwat, Honsawek, Sittisak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098941/
https://www.ncbi.nlm.nih.gov/pubmed/30128216
http://dx.doi.org/10.7717/peerj.5492