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Alu hypermethylation and high oxidative stress in patients with musculoskeletal tumors
BACKGROUND: Alu is one of the non-autonomous element retrotransposons, constituting nearly 11% of the human DNA. Methylation changes of the Alu element can cause genomic instability, a hallmark of cancer development, ultimately leading to the development of cancer. Epigenetic factors may induce the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098941/ https://www.ncbi.nlm.nih.gov/pubmed/30128216 http://dx.doi.org/10.7717/peerj.5492 |