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Subcutaneous administration of a fusion protein composed of pertussis toxin and filamentous hemagglutinin from Bordetella pertussis induces mucosal and systemic immune responses

OBJECTIVE(S): After decades of containment, pertussis disease, caused by Bordetella pertussis seems to be re-emerging and still remains a major cause of reported vaccine-preventable deaths worldwide. The current licensed whole-cell vaccines display reactogenicity while acellular vaccines are expensi...

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Detalles Bibliográficos
Autores principales: Torkashvand, Ali, Bahrami, Fariborz, Adib, Minoo, Ajdary, Soheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098962/
https://www.ncbi.nlm.nih.gov/pubmed/30140416
http://dx.doi.org/10.22038/IJBMS.2018.29112.7026