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CX691, as an AMPA receptor positive modulator, improves the learning and memory in a rat model of Alzheimer’s disease

OBJECTIVE(S): Growing evidence suggests that dysfunction of the glutamatergic system and α-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid (AMPA) receptors are involved in pathology of Alzheimer’s disease (AD). Because AMPA receptors play a key role in plasticity synaptic regulation, positive modu...

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Detalles Bibliográficos
Autores principales: Mozafari, Nazanin, Shamsizadeh, Ali, Fatemi, Iman, Allahtavakoli, Mohammad, Moghadam-Ahmadi, Amir, Kaviani, Elham, Kaeidi, Ayat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098965/
https://www.ncbi.nlm.nih.gov/pubmed/30140412
http://dx.doi.org/10.22038/IJBMS.2018.28544.6934