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Vildagliptin Enhances Differentiation of Insulin Producing Cells from Adipose-Derived Mesenchymal Stem Cells

OBJECTIVE: Type 1 diabetes is caused by destruction of beta cells of pancreas. Vildagliptin (VG), a dipeptidyl peptidase IV (DPP IV) inhibitor, is an anti-diabetic drug, which increases beta cell mass. In the present study, the effects of VG on generation of insulin-producing cells (IPCs) from adipo...

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Detalles Bibliográficos
Autores principales: Karimi, Samaneh, Ai, Jafar, Khorsandi, Layasadat, Bijan Nejad, Darioush, Saki, Ghasem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099143/
https://www.ncbi.nlm.nih.gov/pubmed/30123993
http://dx.doi.org/10.22074/cellj.2019.5542