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Hyperglycemia Promotes Chemoresistance Through the Reduction of the Mitochondrial DNA Damage, the Bax/Bcl-2 and Bax/Bcl-XL Ratio, and the Cells in Sub-G1 Phase Due to Antitumoral Drugs Induced-Cytotoxicity in Human Colon Adenocarcinoma Cells

Diabetes and cancer are common, chronic, and potentially fatal diseases that frequently co-exist. Observational studies clearly indicate that the risk of several types of cancer is increased in diabetic patients and a number of cancer types have shown a higher mortality rate in patients with hypergl...

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Detalles Bibliográficos
Autores principales: Bergandi, Loredana, Mungo, Eleonora, Morone, Rosa, Bosco, Ornella, Rolando, Barbara, Doublier, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099160/
https://www.ncbi.nlm.nih.gov/pubmed/30150934
http://dx.doi.org/10.3389/fphar.2018.00866