You Are What You (First) Eat

As far back as we can remember, we eat. In fact, we eat before we can remember. Our first meal is amniotic fluid. We swallow it during the first trimester of gestation, and with that, we expose our gut to a universe of molecules. These early molecules have a profound influence on gut and brain funct...

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Autores principales: Buchanan, Kelly L., Bohórquez, Diego V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099179/
https://www.ncbi.nlm.nih.gov/pubmed/30150928
http://dx.doi.org/10.3389/fnhum.2018.00323
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author Buchanan, Kelly L.
Bohórquez, Diego V.
author_facet Buchanan, Kelly L.
Bohórquez, Diego V.
author_sort Buchanan, Kelly L.
collection PubMed
description As far back as we can remember, we eat. In fact, we eat before we can remember. Our first meal is amniotic fluid. We swallow it during the first trimester of gestation, and with that, we expose our gut to a universe of molecules. These early molecules have a profound influence on gut and brain function. For example, the taste of the amniotic fluid changes based on the mother’s diet. Indeed, recent findings suggest that food preferences begin in utero. Likewise, a baby’s first exposure to bacteria, previously thought to be during birth, appears to be in utero as well. And just as postnatal food and microbiota are implicated in brain function and dysfunction, prenatal nutrients and microbes may have a long-lasting impact on the development of the gut-brain neural circuits processing food, especially considering their plasticity during this vulnerable period. Here, we use current literature to put forward concepts needed to understand how the gut first meets the brain, and how this encounter may help us remember food.
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spelling pubmed-60991792018-08-27 You Are What You (First) Eat Buchanan, Kelly L. Bohórquez, Diego V. Front Hum Neurosci Neuroscience As far back as we can remember, we eat. In fact, we eat before we can remember. Our first meal is amniotic fluid. We swallow it during the first trimester of gestation, and with that, we expose our gut to a universe of molecules. These early molecules have a profound influence on gut and brain function. For example, the taste of the amniotic fluid changes based on the mother’s diet. Indeed, recent findings suggest that food preferences begin in utero. Likewise, a baby’s first exposure to bacteria, previously thought to be during birth, appears to be in utero as well. And just as postnatal food and microbiota are implicated in brain function and dysfunction, prenatal nutrients and microbes may have a long-lasting impact on the development of the gut-brain neural circuits processing food, especially considering their plasticity during this vulnerable period. Here, we use current literature to put forward concepts needed to understand how the gut first meets the brain, and how this encounter may help us remember food. Frontiers Media S.A. 2018-08-13 /pmc/articles/PMC6099179/ /pubmed/30150928 http://dx.doi.org/10.3389/fnhum.2018.00323 Text en Copyright © 2018 Buchanan and Bohórquez. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Buchanan, Kelly L.
Bohórquez, Diego V.
You Are What You (First) Eat
title You Are What You (First) Eat
title_full You Are What You (First) Eat
title_fullStr You Are What You (First) Eat
title_full_unstemmed You Are What You (First) Eat
title_short You Are What You (First) Eat
title_sort you are what you (first) eat
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099179/
https://www.ncbi.nlm.nih.gov/pubmed/30150928
http://dx.doi.org/10.3389/fnhum.2018.00323
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