Interleukin-6 and Type-I Collagen Production by Systemic Sclerosis Fibroblasts Are Differentially Regulated by Interleukin-17A in the Presence of Transforming Growth Factor-Beta 1

Functional cytokine networks have been poorly characterized in systemic sclerosis (SSc). While interleukin-17A (IL-17A) is increased in SSc skin and other organs, its role is still debated, particularly considering fibrogenesis. We uncover here a dual function of IL-17A in the presence of transformi...

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Detalles Bibliográficos
Autores principales: Dufour, Aleksandra Maria, Alvarez, Montserrat, Russo, Barbara, Chizzolini, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099180/
https://www.ncbi.nlm.nih.gov/pubmed/30150989
http://dx.doi.org/10.3389/fimmu.2018.01865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099180/
https://www.ncbi.nlm.nih.gov/pubmed/30150989
http://dx.doi.org/10.3389/fimmu.2018.01865

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