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T-Cell Leukemia/Lymphoma 1 (TCL1): An Oncogene Regulating Multiple Signaling Pathways

Almost 30 years ago, Carlo Croce's group discovered the T-Cell Leukemia/Lymphoma 1A oncogene (TCL1A or TCL1). TCL1 protein is normally expressed in fetal tissues and early developmental stage lymphocytes. Its expression is deregulated in chronic lymphocytic leukemia (B-CLL) and most lymphomas....

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Detalles Bibliográficos
Autores principales: Paduano, Francesco, Gaudio, Eugenio, Mensah, Afua A., Pinton, Sandra, Bertoni, Francesco, Trapasso, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099186/
https://www.ncbi.nlm.nih.gov/pubmed/30151355
http://dx.doi.org/10.3389/fonc.2018.00317