Cargando…

T-Cell Leukemia/Lymphoma 1 (TCL1): An Oncogene Regulating Multiple Signaling Pathways

Almost 30 years ago, Carlo Croce's group discovered the T-Cell Leukemia/Lymphoma 1A oncogene (TCL1A or TCL1). TCL1 protein is normally expressed in fetal tissues and early developmental stage lymphocytes. Its expression is deregulated in chronic lymphocytic leukemia (B-CLL) and most lymphomas....

Descripción completa

Detalles Bibliográficos
Autores principales:	Paduano, Francesco, Gaudio, Eugenio, Mensah, Afua A., Pinton, Sandra, Bertoni, Francesco, Trapasso, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099186/ https://www.ncbi.nlm.nih.gov/pubmed/30151355 http://dx.doi.org/10.3389/fonc.2018.00317

Ejemplares similares

The Tumour Suppressor Fhit Protein Activates C-Raf Ubiquitination and Degradation in Human Melanoma Cells by Interacting with Hsp90
por: Paduano, Francesco, et al.
Publicado: (2022)

The Fhit protein: an opportunity to overcome chemoresistance
por: Gaudio, Eugenio, et al.
Publicado: (2016)

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response
por: Mensah, Afua Adjeiwaa, et al.
Publicado: (2014)

A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells
por: Gaudio, Eugenio, et al.
Publicado: (2016)

Functional Analysis of Tcl1 Using Tcl1-Deficient Mouse Embryonic Stem Cells
por: Miyazaki, Tatsushi, et al.
Publicado: (2013)

Correction: Functional Analysis of Tcl1 Using Tcl1-Deficient Mouse Embryonic Stem Cells
por: Miyazaki, Tatsushi, et al.
Publicado: (2013)

Crystal Structure of Murine Tcl1 Oncoprotein and Conserved Surface Features of the Molecules of the Tcl1 Family
por: Petock, John M., et al.
Publicado: (2002)

DNA Copy Number Changes in Diffuse Large B Cell Lymphomas
por: Cascione, Luciano, et al.
Publicado: (2020)

Protooncogene TCL1b functions as an Akt kinase co-activator that exhibits oncogenic potency in vivo
por: Hashimoto, M, et al.
Publicado: (2013)

TCL1 transgenic mice as a model for CD49d-high chronic lymphocytic leukemia
por: Szenes, Eva, et al.
Publicado: (2020)

Effective Tcl/Tk programming: writing better programs with Tcl and Tk
por: Harrison, Mark, et al.
Publicado: (1998)

Tcl and the Tk toolkit /
por: Ousterhout, John K.
Publicado: (1994)

Tcl and the Tk toolkit
por: Ousterhout, John K
Publicado: (1994)

Tcl/Tk tools
por: Harrison, M, et al.
Publicado: (1997)

Tcl and the Tk toolkit
por: Ousterhout, John K, et al.
Publicado: (2009)

The WNT Pathway Is Relevant for the BCR-ABL1-Independent Resistance in Chronic Myeloid Leukemia
por: Grassi, Susanna, et al.
Publicado: (2019)

Absence of TCL1A expression is a useful diagnostic feature in splenic marginal zone lymphoma
por: Munari, Enrico, et al.
Publicado: (2012)

Expression of the TCL1 Gene at 14q32 in B‐Cell Malignancies but Not in Adult T‐Cell Leukemia
por: Takizawa, Jun, et al.
Publicado: (1998)

Evidence for Non-Cancer-Specific T Cell Exhaustion in the Tcl1 Mouse Model for Chronic Lymphocytic Leukemia
por: Parigger, Thomas, et al.
Publicado: (2021)

Practical programming in Tcl and Tk
por: Welch, Brent B, et al.
Publicado: (2003)

Tcl/Tk in a Nutshell
por: Raines, Paul, et al.
Publicado: (2009)

Practical programming in Tcl and Tk
por: Welch, Brent B
Publicado: (1995)

Tcl 85 Network Programming
por: Kocjan, Wojciech, et al.
Publicado: (2010)

TclTk Pocket Reference
por: Raines, Paul
Publicado: (1998)

Practical programming in Tcl & Tk
por: Welch, Brent B
Publicado: (2000)

Organometallic nucleosides induce non-classical leukemic cell death that is mitochondrial-ROS dependent and facilitated by TCL1-oncogene burden
por: Prinz, Christian, et al.
Publicado: (2015)

Bromodomain and extra-terminal domain inhibition modulates the expression of pathologically relevant microRNAs in diffuse large B-cell lymphoma
por: Mensah, Afua A., et al.
Publicado: (2018)

A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis
por: Bilotta, Anna, et al.
Publicado: (2016)

Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma
por: Chilà, Rosaria, et al.
Publicado: (2014)

Mitochondrial Ca(2+) Remodeling is a Prime Factor in Oncogenic Behavior
por: Rimessi, Alessandro, et al.
Publicado: (2015)

Combined ibrutinib and venetoclax treatment vs single agents in the TCL1 mouse model of chronic lymphocytic leukemia
por: Kater, Arnon P., et al.
Publicado: (2021)

Editorial: New insights into the mechanisms of resistance to anti-cancer drugs
por: Bertoni, Francesco, et al.
Publicado: (2022)

ASB2 is a direct target of FLI1 that sustains NF-κB pathway activation in germinal center-derived diffuse large B-cell lymphoma
por: Sartori, Giulio, et al.
Publicado: (2021)

BET bromodomain inhibitor birabresib in mantle cell lymphoma: in vivo activity and identification of novel combinations to overcome adaptive resistance
por: Tarantelli, Chiara, et al.
Publicado: (2018)

IDO1-Targeted Therapy Does Not Control Disease Development in the Eµ-TCL1 Mouse Model of Chronic Lymphocytic Leukemia
por: Öztürk, Selcen, et al.
Publicado: (2021)

Case Report: Identification of a Novel Pathogenic Germline TP53 Variant in a Family With Li–Fraumeni Syndrome
por: Paduano, Francesco, et al.
Publicado: (2021)

TcL Scripting for Cisco IOS
por: Blair, Raymond, et al.
Publicado: (2010)

TclTk 85 Programming Cookbook
por: Wheeler, Bert
Publicado: (2011)

3rd Tcl/Tk Workshop
por: USENIX Association. Berkeley
Publicado: (1995)

Tcl/Tk: a developer's guide
por: Flynt, Clif
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_d6lhc8g0kuvcnv6r2i49en72f6