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Natural biological variation of white matter microstructure is accentuated in Huntington's disease

Huntington's disease (HD) is a monogenic neurodegenerative disorder caused by a CAG‐repeat expansion in the Huntingtin gene. Presence of this expansion signifies certainty of disease onset, but only partly explains age at which onset occurs. Genome‐wide association studies have shown that natur...

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Detalles Bibliográficos
Autores principales: Gregory, Sarah, Crawford, Helen, Seunarine, Kiran, Leavitt, Blair, Durr, Alexandra, Roos, Raymund A. C., Scahill, Rachael I., Tabrizi, Sarah J., Rees, Geraint, Langbehn, Douglas, Orth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099203/
https://www.ncbi.nlm.nih.gov/pubmed/29682858
http://dx.doi.org/10.1002/hbm.24191