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Stereocontrolled Synthesis of 2‐Fluorinated C‐Glycosides

A systematic study of the addition of C‐based nucleophiles to fluorinated lactones based on 2‐deoxy‐2‐fluoro‐d‐pyranoses is disclosed. This high yielding, α‐selective process was found to be independent on the nature or configuration [(R)‐C(sp(3))–F, (S)‐C(sp(3))–F] of the substituent at C2. Represe...

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Detalles Bibliográficos
Autores principales: Sadurní, Anna, Gilmour, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099233/
https://www.ncbi.nlm.nih.gov/pubmed/30147438
http://dx.doi.org/10.1002/ejoc.201800618