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Morphological and functional analyses of skeletal muscles from an immunodeficient animal model of limb‐girdle muscular dystrophy type 2E

Introduction: Limb‐girdle muscular dystrophy type 2E (LGMD2E) is caused by mutations in the β‐sarcoglycan gene, which is expressed in skeletal, cardiac, and smooth muscles. β‐Sarcoglycan‐deficient (Sgcb‐null) mice develop severe muscular dystrophy and cardiomyopathy with focal areas of necrosis. Met...

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Detalles Bibliográficos
Autores principales: Giovannelli, Gaia, Giacomazzi, Giorgia, Grosemans, Hanne, Sampaolesi, Maurilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099247/
https://www.ncbi.nlm.nih.gov/pubmed/29476695
http://dx.doi.org/10.1002/mus.26112