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Caveolin 3‐dependent loss of t‐tubular I (Ca) during hypertrophy and heart failure in mice

NEW FINDINGS: What is the central question of this study? Heart failure is associated with redistribution of L‐type Ca(2+) current (I (Ca)) away from the t‐tubule membrane to the surface membrane of cardiac ventricular myocytes. However, the underlying mechanism and its dependence on severity of pat...

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Detalles Bibliográficos
Autores principales: Bryant, Simon M., Kong, Cherrie H. T., Watson, Judy J., Gadeberg, Hanne C., James, Andrew F., Cannell, Mark B., Orchard, Clive H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099270/
https://www.ncbi.nlm.nih.gov/pubmed/29473235
http://dx.doi.org/10.1113/EP086731