Melatonin prevents Drp1‐mediated mitochondrial fission in diabetic hearts through SIRT1‐PGC1α pathway

Myocardial contractile dysfunction is associated with an increase in mitochondrial fission in patients with diabetes. However, whether mitochondrial fission directly promotes diabetes‐induced cardiac dysfunction is still unknown. Melatonin exerts a substantial influence on the regulation of mitochon...

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Detalles Bibliográficos
Autores principales: Ding, Mingge, Feng, Na, Tang, Daishi, Feng, Jiahao, Li, Zeyang, Jia, Min, Liu, Zhenhua, Gu, Xiaoming, Wang, Yuemin, Fu, Feng, Pei, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099285/
https://www.ncbi.nlm.nih.gov/pubmed/29575122
http://dx.doi.org/10.1111/jpi.12491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099285/
https://www.ncbi.nlm.nih.gov/pubmed/29575122
http://dx.doi.org/10.1111/jpi.12491

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