Cargando…
Melatonin prevents Drp1‐mediated mitochondrial fission in diabetic hearts through SIRT1‐PGC1α pathway
Myocardial contractile dysfunction is associated with an increase in mitochondrial fission in patients with diabetes. However, whether mitochondrial fission directly promotes diabetes‐induced cardiac dysfunction is still unknown. Melatonin exerts a substantial influence on the regulation of mitochon...
Autores principales: | Ding, Mingge, Feng, Na, Tang, Daishi, Feng, Jiahao, Li, Zeyang, Jia, Min, Liu, Zhenhua, Gu, Xiaoming, Wang, Yuemin, Fu, Feng, Pei, Jianming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099285/ https://www.ncbi.nlm.nih.gov/pubmed/29575122 http://dx.doi.org/10.1111/jpi.12491 |
Ejemplares similares
-
Sirt6 deficiency contributes to mitochondrial fission and oxidative damage in podocytes via ROCK1‐Drp1 signalling pathway
por: Chen, Zhaowei, et al.
Publicado: (2022) -
PDI-mediated S-nitrosylation of DRP1 facilitates DRP1-S616 phosphorylation and mitochondrial fission in CA1 neurons
por: Lee, Duk-shin, et al.
Publicado: (2018) -
The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1
por: Liu, Raymond, et al.
Publicado: (2015) -
A role for septin 2 in Drp1‐mediated mitochondrial fission
por: Pagliuso, Alessandro, et al.
Publicado: (2016) -
Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport
por: Ramonett, Aaron, et al.
Publicado: (2022)