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Enhanced expression of thioredoxin‐interacting‐protein regulates oxidative DNA damage and aging

The “free radical theory of aging” suggests that reactive oxygen species (ROS) are responsible for age‐related loss of cellular functions and, therefore, represent the main cause of aging. Redox regulation by thioredoxin‐1 (TRX) plays a crucial role in responses to oxidative stress. We show that thi...

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Detalles Bibliográficos
Autores principales: Oberacker, Tina, Bajorat, Jörg, Ziola, Sabine, Schroeder, Anne, Röth, Daniel, Kastl, Lena, Edgar, Bruce A., Wagner, Wolfgang, Gülow, Karsten, Krammer, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099297/
https://www.ncbi.nlm.nih.gov/pubmed/29897613
http://dx.doi.org/10.1002/1873-3468.13156