Derivation of a no‐significant‐risk‐level for tetrabromobisphenol A based on a threshold non‐mutagenic cancer mode of action

A no‐significant‐risk‐level of 20 mg day(–1) was derived for tetrabromobisphenol A (TBBPA). Uterine tumors (adenomas, adenocarcinomas, and malignant mixed Müllerian) observed in female Wistar Han rats from a National Toxicology Program 2‐year cancer bioassay were identified as the critical effect. S...

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Detalles Bibliográficos
Autores principales: Pecquet, Alison M., Martinez, Jeanelle M., Vincent, Melissa, Erraguntla, Neeraja, Dourson, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099322/
https://www.ncbi.nlm.nih.gov/pubmed/29441599
http://dx.doi.org/10.1002/jat.3594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099322/
https://www.ncbi.nlm.nih.gov/pubmed/29441599
http://dx.doi.org/10.1002/jat.3594

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