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Derivation of a no‐significant‐risk‐level for tetrabromobisphenol A based on a threshold non‐mutagenic cancer mode of action
A no‐significant‐risk‐level of 20 mg day(–1) was derived for tetrabromobisphenol A (TBBPA). Uterine tumors (adenomas, adenocarcinomas, and malignant mixed Müllerian) observed in female Wistar Han rats from a National Toxicology Program 2‐year cancer bioassay were identified as the critical effect. S...
Autores principales: | Pecquet, Alison M., Martinez, Jeanelle M., Vincent, Melissa, Erraguntla, Neeraja, Dourson, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099322/ https://www.ncbi.nlm.nih.gov/pubmed/29441599 http://dx.doi.org/10.1002/jat.3594 |
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