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Semisynthesis, Characterization and Evaluation of New Adenosine Derivatives as Antiproliferative Agents

We describe the semisynthesis and biological effects of adenosine derivatives, which were anticipated to function as agonists for the A(3) receptor. Molecular docking was used to select candidate compounds. Fifteen nucleoside derivatives were obtained through nucleophilic substitutions of the N(6)-p...

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Detalles Bibliográficos
Autores principales: Valdés Zurita, Francisco, Brown Vega, Nelson, Gutiérrez Cabrera, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099407/
https://www.ncbi.nlm.nih.gov/pubmed/29738449
http://dx.doi.org/10.3390/molecules23051111