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Semisynthesis, Characterization and Evaluation of New Adenosine Derivatives as Antiproliferative Agents
We describe the semisynthesis and biological effects of adenosine derivatives, which were anticipated to function as agonists for the A(3) receptor. Molecular docking was used to select candidate compounds. Fifteen nucleoside derivatives were obtained through nucleophilic substitutions of the N(6)-p...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099407/ https://www.ncbi.nlm.nih.gov/pubmed/29738449 http://dx.doi.org/10.3390/molecules23051111 |