Spared CA1 pyramidal neuron function and hippocampal performance following antisense knockdown of microRNA‐134

OBJECTIVE: Inhibition of microRNA‐134 by an oligonucleotide antagomir (ant‐134) has been shown to produce powerful antiseizure effects in multiple models of epilepsy. However, to successfully translate the treatment to the clinic, it is important to assess what potential adverse effects it may have...

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Detalles Bibliográficos
Autores principales: Morris, Gareth, Brennan, Gary P., Reschke, Cristina R., Henshall, David C., Schorge, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full‐length Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099438/
https://www.ncbi.nlm.nih.gov/pubmed/29978460
http://dx.doi.org/10.1111/epi.14475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099438/
https://www.ncbi.nlm.nih.gov/pubmed/29978460
http://dx.doi.org/10.1111/epi.14475

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