Pharmacokinetics, Pharmacodynamics, and Tolerability of Concomitant Multiple Dose Administration of Verinurad (RDEA3170) and Allopurinol in Adult Male Subjects With Gout

Verinurad (RDEA3170) is a selective uric acid reabsorption inhibitor in clinical development for treatment of hyperuricemia and gout. This phase 1b, multiple‐dose, drug‐drug interaction study evaluated the pharmacokinetics, pharmacodynamics, and tolerability of verinurad in combination with allopuri...

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Detalles Bibliográficos
Autores principales: Kankam, Martin, Hall, Jesse, Gillen, Michael, Yang, Xiaojuan, Shen, Zancong, Lee, Caroline, Liu, Sha, Miner, Jeffrey N., Walker, Susan, Clauson, Vicki, Wilson, David, Nguyen, Mai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Pharmacokinetics/Pharmacodynamics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099444/
https://www.ncbi.nlm.nih.gov/pubmed/29733447
http://dx.doi.org/10.1002/jcph.1119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099444/
https://www.ncbi.nlm.nih.gov/pubmed/29733447
http://dx.doi.org/10.1002/jcph.1119

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