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Stabilising Peptoid Helices Using Non‐Chiral Fluoroalkyl Monomers

Stability towards protease degradation combined with modular synthesis has made peptoids of considerable interest in the fields of chemical biology, medicine, and biomaterials. Given their tertiary amide backbone, peptoids lack the capacity to hydrogen‐bond, and as such, controlling secondary struct...

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Detalles Bibliográficos
Autores principales: Gimenez, Diana, Aguilar, Juan A., Bromley, Elizabeth H. C., Cobb, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099454/
https://www.ncbi.nlm.nih.gov/pubmed/29846037
http://dx.doi.org/10.1002/anie.201804488