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The application of transcriptional benchmark dose modeling for deriving thresholds of effects associated with solar‐simulated ultraviolet radiation exposure

Considerable data has been generated to elucidate the transcriptional response of cells to ultraviolet radiation (UVR) exposure providing a mechanistic understanding of UVR‐induced cellular responses. However, using these data to support standards development has been challenging. In this study, we...

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Detalles Bibliográficos
Autores principales: Qutob, Sami S., Chauhan, Vinita, Kuo, Byron, Williams, Andrew, Yauk, Carole L., McNamee, James P., Gollapudi, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099464/
https://www.ncbi.nlm.nih.gov/pubmed/29761935
http://dx.doi.org/10.1002/em.22196