Exposure‐safety and efficacy response relationships and population pharmacokinetics of eslicarbazepine acetate

OBJECTIVES: Eslicarbazepine acetate (ESL) is a once‐daily (QD) oral antiepileptic drug (AED) for focal‐onset seizures (FOS). Pharmacokinetic (PK) and pharmacodynamic (PD) models were developed to assess dose selection, identify significant AED drug interactions, and quantitate relationships between...

Descripción completa

Detalles Bibliográficos
Autores principales: Gidal, B. E., Jacobson, M. P., Ben‐Menachem, E., Carreño, M., Blum, D., Soares‐da‐Silva, P., Falcão, A., Rocha, F., Moreira, J., Grinnell, T., Ludwig, E., Fiedler‐Kelly, J., Passarell, J., Sunkaraneni, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099471/
https://www.ncbi.nlm.nih.gov/pubmed/29732549
http://dx.doi.org/10.1111/ane.12950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099471/
https://www.ncbi.nlm.nih.gov/pubmed/29732549
http://dx.doi.org/10.1111/ane.12950

Ejemplares similares