Non‐enzymatic cross‐linking of collagen type II fibrils is tuned via osmolality switch

An important aspect in cartilage ageing is accumulation of advanced glycation end products (AGEs) after exposure to sugars. Advanced glycation results in cross‐links formation between the collagen fibrils in articular cartilage, hampering their flexibility and making cartilage more brittle. In the c...

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Detalles Bibliográficos
Autores principales: Pouran, Behdad, Moshtagh, Parisa R., Arbabi, Vahid, Snabel, Jessica, Stoop, Reinout, Ruberti, Jeffrey, Malda, Jos, Zadpoor, Amir A., Weinans, Harrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099510/
https://www.ncbi.nlm.nih.gov/pubmed/29334127
http://dx.doi.org/10.1002/jor.23857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099510/
https://www.ncbi.nlm.nih.gov/pubmed/29334127
http://dx.doi.org/10.1002/jor.23857

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