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Resolution Matters: Correlating Quantitative Proteomics and Nanoscale‐Precision Microscopy for Reconstructing Synapse Identity

For more than a century, the precision at which any protein (or RNA) could be localized in living cells depends on the spatial resolution of microscopy. Light microscopy, even recently benchmarked laser‐scanning microscopy, is inherently liable to the diffraction limit of visible light. Electron mic...

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Detalles Bibliográficos
Autores principales: Miklosi, Andras Gabor, Del Favero, Giorgia, Marko, Doris, Harkany, Tibor, Lubec, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099515/
https://www.ncbi.nlm.nih.gov/pubmed/29932496
http://dx.doi.org/10.1002/pmic.201800139