[(18)F]FEPPA a TSPO Radioligand: Optimized Radiosynthesis and Evaluation as a PET Radiotracer for Brain Inflammation in a Peripheral LPS-Injected Mouse Model

[(18)F]FEPPA is a specific ligand for the translocator protein of 18 kDa (TSPO) used as a positron emission tomography (PET) biomarker for glial activation and neuroinflammation. [(18)F]FEPPA radiosynthesis was optimized to assess in a mouse model the cerebral inflammation induced by an intraperiton...

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Detalles Bibliográficos
Autores principales: Vignal, Nicolas, Cisternino, Salvatore, Rizzo-Padoin, Nathalie, San, Carine, Hontonnou, Fortune, Gelé, Thibaut, Declèves, Xavier, Sarda-Mantel, Laure, Hosten, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099542/
https://www.ncbi.nlm.nih.gov/pubmed/29875332
http://dx.doi.org/10.3390/molecules23061375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099542/
https://www.ncbi.nlm.nih.gov/pubmed/29875332
http://dx.doi.org/10.3390/molecules23061375

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