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Epitopes of MUC1 Tandem Repeats in Cancer as Revealed by Antibody Crystallography: Toward Glycopeptide Signature-Guided Therapy

Abnormally O-glycosylated MUC1 tandem repeat glycopeptide epitopes expressed by multiple types of cancer have long been attractive targets for therapy in the race against genetic mutations of tumor cells. Glycopeptide signature-guided therapy might be a more promising avenue than mutation signature-...

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Detalles Bibliográficos
Autores principales: Zhou, Dapeng, Xu, Lan, Huang, Wei, Tonn, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099590/
https://www.ncbi.nlm.nih.gov/pubmed/29857542
http://dx.doi.org/10.3390/molecules23061326