Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins

BACKGROUND: In order to ensure precise chromosome duplication, eukaryotes "license" their replication origins during late mitosis and early G1 by assembling complexes of Mcm2-7 onto them. Mcm2-7 are essential for DNA replication, but are displaced from origins as they initiate, thus ensuri...

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Detalles Bibliográficos
Autores principales: Gillespie, Peter J, Li, Anatoliy, Blow, J Julian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC60996/
https://www.ncbi.nlm.nih.gov/pubmed/11737877
http://dx.doi.org/10.1186/1471-2091-2-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC60996/
https://www.ncbi.nlm.nih.gov/pubmed/11737877
http://dx.doi.org/10.1186/1471-2091-2-15

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