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Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins
BACKGROUND: In order to ensure precise chromosome duplication, eukaryotes "license" their replication origins during late mitosis and early G1 by assembling complexes of Mcm2-7 onto them. Mcm2-7 are essential for DNA replication, but are displaced from origins as they initiate, thus ensuri...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC60996/ https://www.ncbi.nlm.nih.gov/pubmed/11737877 http://dx.doi.org/10.1186/1471-2091-2-15 |