(−)-Epigallocatechin 3-Gallate Synthetic Analogues Inhibit Fatty Acid Synthase and Show Anticancer Activity in Triple Negative Breast Cancer

(−)-Epigallocatechin 3-gallate (EGCG) is a natural polyphenol from green tea with reported anticancer activity and capacity to inhibit the lipogenic enzyme fatty acid synthase (FASN), which is overexpressed in several human carcinomas. To improve the pharmacological profile of EGCG, we previously de...

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Detalles Bibliográficos
Autores principales: Crous-Masó, Joan, Palomeras, Sònia, Relat, Joana, Camó, Cristina, Martínez-Garza, Úrsula, Planas, Marta, Feliu, Lidia, Puig, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099607/
https://www.ncbi.nlm.nih.gov/pubmed/29751678
http://dx.doi.org/10.3390/molecules23051160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099607/
https://www.ncbi.nlm.nih.gov/pubmed/29751678
http://dx.doi.org/10.3390/molecules23051160

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