Identfication of Potent LXRβ-Selective Agonists without LXRα Activation by In Silico Approaches

Activating Liver X receptors (LXRs) represents a promising therapeutic option for dyslipidemia. However, activating LXRα may cause undesired lipogenic effects. Discovery of highly LXRβ-selective agonists without LXRα activation were indispensable for dyslipidemia. In this study, in silico approaches...

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Detalles Bibliográficos
Autores principales: Chen, Meimei, Yang, Fafu, Kang, Jie, Gan, Huijuan, Yang, Xuemei, Lai, Xinmei, Gao, Yuxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099648/
https://www.ncbi.nlm.nih.gov/pubmed/29867043
http://dx.doi.org/10.3390/molecules23061349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099648/
https://www.ncbi.nlm.nih.gov/pubmed/29867043
http://dx.doi.org/10.3390/molecules23061349

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