Novel-Substituted Heterocyclic GABA Analogues. Enzymatic Activity against the GABA-AT Enzyme from Pseudomonas fluorescens and In Silico Molecular Modeling

γ-Aminobutyric acid (GABA) is the most important inhibitory neurotransmitter in the central nervous system, and a deficiency of GABA is associated with serious neurological disorders. Due to its low lipophilicity, there has been an intensive search for new molecules with increased lipophilicity to c...

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Detalles Bibliográficos
Autores principales: Tovar-Gudiño, Erika, Guevara-Salazar, Juan Alberto, Bahena-Herrera, José Raúl, Trujillo-Ferrara, José Guadalupe, Martínez-Campos, Zuleyma, Razo-Hernández, Rodrigo Said, Santiago, Ángel, Pastor, Nina, Fernández-Zertuche, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099672/
https://www.ncbi.nlm.nih.gov/pubmed/29747438
http://dx.doi.org/10.3390/molecules23051128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099672/
https://www.ncbi.nlm.nih.gov/pubmed/29747438
http://dx.doi.org/10.3390/molecules23051128

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