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Combining New Non-Nucleoside Reverse Transcriptase Inhibitors (RTIs) with AZT Results in Strong Synergism against Multi-RTI-Resistant HIV-1 Strains

Reverse transcriptase inhibitors (RTIs), including nucleoside RTIs (NRTIs) and non-nucleoside RTIs (NNRTIs), are critical antiretroviral drugs for the treatment of human immunodeficiency virus (HIV) infection. Emergence of multi-RTI resistance calls for the development of more potent therapeutics or...

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Detalles Bibliográficos
Autores principales: Yu, Fei, Li, Wen, Wang, Lili, Dai, Yu, Lu, Xin, Wang, Qian, Xie, Lan, Jiang, Shibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099689/
https://www.ncbi.nlm.nih.gov/pubmed/30004408
http://dx.doi.org/10.3390/molecules23071599